Elisabet Marti and José Luís Balcázar, researchers of the Quality and Microbial diversity line of the Water Quality Area of ICRA, published a study on the characterization of a novel multiresistant bacteria of the genus Aeromonas isolated in the River Ter in Ripoll (Girona) at Clinical Microbiology and Infection.

In recent years several studies have been published, which involved researchers from the Catalan Institute for Water Research (ICRA), the presence of antibiotics in Spanish rivers. Today provide evidence of how these antibiotics affect aquatic organisms and give rise to a new bacterium. A recent investigation of the ICRA determines the presence of antibiotics affects the appearance and spread of a new antibiotic multiresistant bacteria in the aquatic environment.

Antibiotics are the main weapon to our health system has to fend off the bacteria responsible for a host of diseases. These bacteria, however, developed different mechanisms to resist the effects of antibiotics produced by them. These resistance mechanisms are also easily exchanged between members of the microbial community, which is evolutionarily very advantageous for them, but it is a real threat from a clinical and epidemiological point of view. Bacterial resistance to antibiotics is therefore a serious public health problem because it is increasingly common these compounds, effective until recently, ineffective or dangerous to many pathogens.

In recent decades, studies on the transfer of resistance genes have focused almost exclusively on bacteria of clinical interest, and has ignored the role that bacteria of environmental origin may have on this process. That's why researchers at the Catalan Institute for Water Research (ICRA), Elisabet Marti and José Luís Balcázar have conducted an investigation to determine the effect of human activities on the emergence and spread of resistance to antibiotics in the aquatic environment.

Some of these investigations by the Catalan Institute for Water Research (ICRA), financed by the Ministry of Economy and Competitiveness and the European Regional Development Fund (ERDF), have been published in Clinical Microbiology and Infection. The study entitled "Multidrug resistance-encoding plasmid from Aeromonas" present the characterization of a new bacterial species of the genus Aeromonas isolated at the River Ter as it passes through Ripoll (Girona). This bacterium is resistant to most antibiotics commonly used in hospitals and outpatient, including aminoglycosoides (Kanamycin and gentamicin), beta-lactam (amoxicillin and ceftazidime), fluoroquinolones (ciprofloxacin, enrofloxacin, norfloxacin and ofloxacin) and sulfonamides (sulfamethoxazole), among others.

The presence of resistant bacteria in the environment therefore represents an added concern because of the environmental and clinical implications derived. These include the increasing restrictions on the use of effective drugs and the need to use antibiotics more expensive and broader spectrum of action.

Ultimately, a greater and more accurate understanding of the pathways involved in the dissemination of this resistance, the regulation and the factors that stimulate are key strategies to establish effective control and counter the emergence of resistance in pathogenic bacteria .

Clinical Microbiology and Infection, 18 (2012), E366-E368

Multidrug resistance-encoding plasmid from Aeromonas sp. strain P2G1


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